Experience with VDRL Flocculation Antigen in the Kolmer Complement Fixation Test

The VDRL tube flocculation test; a microflocculation test for syphilis using cardiolipin-lecithin-cholesterol antigen.

In an earlier paper in this Journal (Vogelsang, 1947), a new microflocculation test for syphilis described by Harris, Rosenberg, and Riedel (1946) was compared with the Wassermann reaction, the Kahn standard test, and the Meinicke clarification test in 5,556 sera. The test was found to be very useful in the diagnosis of syphilis, having a satisfactory sensitivity and a good specificity. Harris ...

Detection of rotavirus by Latex Agglutination Test (Rotales); Comparison with Electron Microscopy and Complement Fixation Test

V.D.R.L., Eagle, Price, and Kolmer tests; a comparison using 1,029 South African Bantu sera.

As no published results were available of valid evaluations of common serological reactions found amongst the various racial groups of South Africa, the serological department of the Natal Pathological Service initiated a comprehensive investigation of these reactions in the racial groups of Natal. It is hoped to publish the results in a series of papers. This paper reports the results of testi...

Complement Fixation in Kala-Azar with the WKK Antigen

In our present issue we publish two articles in which the value of a complement-fixation test in early diagnosis of kala-azar is stressed. The antigen used is that of Witebsky, Klingenstein and Kuhn prepared from the tubercle bacillus, and originally intended for complement-fixation tests in tuberculosis. In tuberculosis, however, the results are very poor. Work in South America, however, revea...

Quantitative micro-complement fixation test.

A quantitative micro-complement fixation test capable of detecting nanogram quantities of antigen is described. The test is simple to perform and is highly reproducible. Typical results from three antigen-antibody systems are given.